There are already more than hundreds of hormones present in the human body. By sending information through your blood to your organs, skin, muscles and other tissues, hormones help your body coordinate various processes.
Most tissues (most glands) that produce and release hormones are part of your endocrine system. In an interview with HT lifestyle, Dr. Varini N, Senior Advisor – Obosteratriist and gynecologist at the Milan Fertility Center in Bangalore, shared, “many body functions, such as metabolism, homeostasis (continuous internal balance), including blood pressure and blood sugar regulation.
He further revealed, “A small amount of hormone can have a large effect. Due to this, even small variations in levels can have a major effect on your body and consequently can result in the result of diseases that require therapy. On the other hand, a hormonal imbalance or extended exposure to specific hormones may increase the chances of developing reproductive malformations. Ovarian hormones such as progesterone and estrogen can increase the risk of ovarian, endometrial and breast cancer between other reproductive cancer. The cell division is affected by hormones, and can result in genetic mutation and accumulation of cancer. ,
Factors that increase the chances of development of reproductive cancer –
1. Breeding pattern: The risk of breast cancer can be given early menstruation, late menopause and never birth.
2. The use of hormone replacement treatment (HRT), especially when estrogen and progestin are combined, can increase the risk of breast cancer.
3. obesity: The risk of endometrial cancer and breast cancer can increase with excessive weight.
4. Endometriosis: Type I is closely associated with ovarian cancer endometriosis.
Axia
The health of the reproductive system depends on hormones such as testosterone, progesterone and estrogen. However, many distortions have been linked to chronic or excessive risk for these hormones:
1. Breast Cancer: Progesterone and estrogen have a major role in the development of breast cancer. The risk for women increases the hormone replacement therapy (HRT) for an extended period of time, has an early menrache, or late menopause. Breast cancer cells that are hormone-sensitive can lead to more rapidly as a result of these hormones.
2. Ovarian cancer: Research indicates that a woman’s opportunity to develop ovarian cancer may be affected by hormonal factors, as if she undergoes the number of ovulatory cycles. Natural balance of hormones such as polycystic ovarian syndrome (PCOS) may also include disorders.
3. Endometrial Cancer: One of the main risk factors for endometrial cancer is the unopposed estrogen exposure, which occurs when progesterone levels are not sufficient to balance estrogen. Because fat cells produce estrogen, the disease is often seen in obese women. Similar effects are seen in PCOS.
4. prostate cancer: A strong version of dihydrotestosterone (DHT), testosterone and testosterone is associated with prostate cancer in men itself. Prostate malignant cells can spread in response to the amount of height of these hormones.
Hormone mechanisms
Hormones affect the risk of cancer in many ways –
1. Cell proliferation: In tissues that are hormone-sensitive, hormone such as testosterone and estrogen encourage cell divisions. The mutation brought by the increased cell division increases the risk of cancer development.
2. DNA damage: Many hormones have the ability to produce metabolites that cause DNA damage and oxidative stress, which can help in the development of cancer.
3. Recepter activation: When hormones connect with special cell receptors, they begin processes that may result in uncontrolled cell division.
4. Immune suppression: Unbalance hormones can make more difficult to identify and eliminate rude cells for the immune system, which promotes the growth of malignant cells.
risk
Dr. Varini N said, “Age, family history, lifestyle options and medical history are some factors that can make hormonal relations worse for reproductive cancer. Due to their cumulative risk for hormones, older individuals develop hormonal deformities to older individuals The results of the hormone exposure can be enhanced by genetic forecasts, such as mutation in BRCA1 or BRCA2.
He said, “Diseases such as PCOS, endometriosis and long -term hormone therapy are increased vulnerability. Estrogen and progesterone, two female sex hormones, are given dose in birth control pills to regulate fertility. The risk of endometrial and ovarian cancer can be reduced by them. On the other hand, they increase the risk of mild cervix and breast cancer. ,
Prevention and quick detection
Increasing awareness and educating people about early signs and symptoms is the most popular and successful preventive strategy. Dr. Varini N concluded, “Hormone levels can be regulated by eating a balanced diet, exercising and keeping a healthy weight. For initial detection, regular screenings such as PSA tests, pelvic examinations and mammograms are important. Preventive interventions such as selective estrogen receptor modulator (SERM) or immunity surgery for high -risk patients can be detected. The risk can be reduced by using oral contraceptives and hormone replacement treatments and under medical supervision. ,
Disclaimer: This article is only for informative purposes and is not an option for professional medical advice. Always consult your doctor with any question about a medical condition.
