Thrombosis thrombocytopenia syndrome (TTS) is a rare but serious condition associated with some COVID-19 vaccines, particularly adenovirus vector vaccines such as AstraZeneca and Johnson & Johnson’s Janssen vaccine.
What is Thrombosis Thrombocytopenia Syndrome (TTS)?
TTS is characterized by blood clotting (thrombosis) along with low levels of platelets (thrombocytopenia), which are essential for blood clotting. This often involves unusual locations for the blood clot, such as in the brain (cerebral venous sinus thrombosis) or the abdomen.
symptoms of tts
Symptoms of TTS may include
severe or persistent headache
blurred vision
difficulty breathing
Pain in chest
swelling in foot
persistent stomach ache
easy bruising or small blood spots under the skin beyond the injection site
Although TTS is rare, it is important for individuals who have received vaccines associated with TTS to be aware of symptoms and seek medical help if they experience any of them within a few weeks of vaccination. Early identification and treatment are important to effectively manage TTS.
“TTS, or thrombosis with thrombocytopenia syndrome, involves low platelet counts as well as blood clots in the brain or other parts of the body. This is a rare event after specific types of vaccines and other causes. According to WHO Adenovirus vector vaccines, in particular, have rarely been associated with this condition, Dr Jayadevan, co-chairman of the National Indian Medical Association (IMA) Covid Task Force in Kerala, told ANI.
“While COVID vaccines have undoubtedly saved lives, these extremely rare but potentially serious immune-mediated events have also been reported in reputable journals,” Dr. Jayadevan said.
Pharmaceutical giant AstraZeneca has admitted that its COVID-19 vaccine may cause a rare side effect called thrombosis with thrombocytopenia syndrome (TTS), according to a report in The Telegraph.
According to a 2023 report on Yalemedicine.org, a blood clot is essentially a gel-like clot of blood. Small blood clots naturally form whenever you cut or scratch your skin to stop bleeding. However, they become dangerous when they grow within a blood vessel, causing thrombosis (where they block blood flow), a condition responsible for 100,000 deaths per year in the United States. “Those clots usually occur in individuals who are bedridden, hospitalized, or have inflammation, infection, or other medical problems related to cancer,” Yale Medicine hematologist Robert Bona, MD, explains.
AstraZeneca admits its Covishield vaccine may cause rare side effects
The Oxford-AstraZeneca COVID vaccine was marketed worldwide under various brand names including Covishield and Vaxjavria.
Serum Institute of India produced the COVID-19 vaccine named Covishield, which is based not on the mRNA platform but on the viral vector platform. The vaccine uses a modified chimpanzee adenovirus, ChAdOx1, to deliver the COVID-19 spike protein into human cells. Although this cold virus cannot infect the recipient, it can effectively instruct the immune system to prepare defenses against similar viruses.
In 2023, the World Health Organization (WHO) reported that thrombosis with thrombocytopenia syndrome (TTS) as a new adverse event following vaccination in individuals vaccinated with COVID-19 non-replicant adenovirus vector-based vaccines. creep into. These include the AstraZeneca COVID-19 ChAdOx-1 vaccine and the Johnson & Johnson (J&J) Janssen COVID-19 Ad26.COV2-S vaccine.
-with agency input
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Published: April 30, 2024, 07:50 am IST
