Peyronie’s disease in men: causes, symptoms, diagnosis, treatment, coping strategies

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Peyronie’s disease is a medical condition in which fibrous scar tissue develops inside the penis, leading to curved and painful erections. Although the exact cause is unclear, it is believed that Peyronie’s disease may be caused by trauma or injury to the penis, leading to local bleeding and subsequent formation of scar tissue.

Peyronie's disease in men: causes, symptoms, diagnosis, treatment, coping strategies (file photo)
Peyronie’s disease in men: causes, symptoms, diagnosis, treatment, coping strategies (file photo)

In an interview with HT Lifestyle, Dr Chirag Bhandari, founder of the Institute of Andrology and Sexual Health (IASH), explained that over time, this scar tissue can cause significant curvature in the penis, erectile dysfunction and discomfort, which affects both physical and emotional health. He elaborates –

Causes and risk factors

The exact cause of Peyronie’s disease is not yet fully understood, but it is believed that several factors contribute to its development:

  • trauma or injuryDirect injury to the penis during sexual intercourse, sports, or an accident can lead to the formation of scar tissue.
  • Genetic predispositionThere is evidence that it has a hereditary component, and some men are more predisposed to the disease.
  • agePeyronie’s disease is more commonly seen in middle-aged and older men, likely due to changes in the elasticity and healing capacity of tissues.
  • connective tissue disordersMen with certain connective tissue disorders, such as Dupuytren’s contracture, have an increased risk of developing Peyronie’s disease.

symptoms

The symptoms of Peyronie’s disease can vary widely among individuals, but common manifestations are as follows:

  • Penis curvatureThe most noticeable symptom is a significant bend or curvature in the penis when erect.
  • PainMen may experience pain during an erection, which can range from mild discomfort to severe pain.
  • erectile dysfunctionThe physical and psychological effects of the disease may cause difficulty achieving or maintaining an erection.
  • scar tissueThe presence of palpable lumps or hard areas on the shaft of the penis.

Diagnosis

Diagnosing Peyronie’s disease typically involves reviewing the patient’s medical history, performing a physical examination, and using imaging tests. During a physical examination, a healthcare provider may feel hardened scar tissue within the penis. Ultrasound imaging may be used to assess the location and extent of the scar tissue, as well as to check for any abnormalities in blood flow.

Treatment Options

The aim of treatment for Peyronie’s disease is to reduce pain, improve the curvature of the penis, and restore sexual function. The choice of treatment depends on the severity of the condition and the degree of discomfort experienced by the patient. Here are some common treatment approaches:

1. Medicine: Oral medications such as pentoxifylline and potassium para-aminobenzoate (Potaba) may help reduce the formation of scar tissue and ease symptoms. In some cases, intralesional injections with medications such as collagenase clostridium histolyticum (Xiaflex) are used to break up scar tissue.

2. Non-surgical therapy,

  • Traction TherapyPenis traction devices can help stretch the penis and reduce curvature over time.
  • Shockwave TherapyLow-intensity shockwave therapy has been explored as a non-invasive option to improve blood flow and break up scar tissue.
  • PRP (Platelet-Rich Plasma) Therapy: PRP involves injecting platelet-rich plasma obtained from the patient’s own blood into the affected area. This treatment takes advantage of the growth factors in the plasma to stimulate healing, reduce penile curvature, and improve sexual function.

3. Surgery: In severe cases, surgical intervention may be necessary. Surgical options include:

  • nesbitt processRemoval or grafting of tissue opposite the scar to straighten the penis.
  • Plaque incision and grafting: Cutting out the plaque and inserting a graft to straighten the penis.
  • Penis implantsIn cases of severe erectile dysfunction, penile implants may provide improvement in both stiffness and curvature.

cope and support

Living with Peyronie’s disease can be challenging both physically and emotionally. Open communication with a healthcare provider, as well as seeking support and counseling from partners, can significantly assist in managing the condition. Support groups and educational resources can also provide valuable information and emotional reassurance.

Peyronie’s disease is a complex condition that can deeply affect a person’s quality of life, but early diagnosis and a customized treatment approach are essential to manage symptoms and improve outcomes. If you suspect you have Peyronie’s disease, consult a healthcare provider for a comprehensive evaluation and personalized treatment plan.

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